stalluri@gitam.edu
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Dr. Talluri Sekhar obtained his M.Sc. from IIT, Delhi and his Ph.D. from Cornell University. Subsequently, he worked as a research fellow in Harvard Medical School. Currently, he is a Professor in GITAM. He applied 2D and 3D NMR spectroscopy for protein structure and protein folding studies, and uses computational methods for the design of drugs and proteins. He has developed novel methods for 2D and 3D NMR spectroscopy, Computer aided Drug Design and Protein Design.
Research Publications
- Molecular Docking and Virtual Screening based prediction of drugs for COVID-19. S Talluri. 2021. Combinatorial Chemistry & High Throughput Screening 24 (5), 716-728. https://doi.org/10.2174/1386207323666200814132149
- An optimized 3D NOESY-HSQC. S Talluri, G Wagner. 1996. Journal of magnetic resonance. Series B 112 (2), 200-205. https://doi.org/10.1006/jmrb.1996.0132
- Structural characterization of a three-disulfide intermediate of ribonuclease A involved in both the folding and unfolding pathways. S Talluri, DM Rothwarf, HA Scheraga. 1994. Biochemistry 33 (34), 10437-10449. https://doi.org/10.1021/bi00200a027
- Computational protein design of bacteriocins based on structural scaffold of aureocin A53. Talluri S. 2019. International Journal of Bioinformatics Research and Applications, 15(2), pp. 129–143. https://doi.org/10.1504/IJBRA.2019.099575
- Distance Geometry with Improved Sampling of Conformational Space for Biomolecular Structure Determination by NMR Spectroscopy and Protein Design. Sekhar Talluri. 2017. Research Journal of Life Sciences, Bioinformatics, Pharmaceutical and Chemical Sciences (RJLBPCS). 3(2) 84-97. https://doi.org/10.26479/2017.0302.08
Expertise
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Computer aided Drug Design
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Computational Protein Design
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Multidimensional homonuclear and heteronuclear NMR spectroscopy of proteins
Authored Books
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Bioanalytical Techniques. 2012. ISBN 9381141703
