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Siva Nageswararao Gajula

Siva Nageswararao Gajula

Assistant Professor

Education

Ph. D.

Experienced pharmaceutical researcher specialized in drug metabolism and pharmacokinetics (DMPK) studies with proficiency in LC-MS/MS analysis. Skilled in small molecule structural characterization, biomarker quantification, and phytoconstituent identification. Holds a Ph.D. from NIPER Hyderabad and M.S. (Pharm.) from NIPER Ahmedabad. Recipient of merit-based scholarships and awards, demonstrating a strong commitment to academic excellence and scientific research.

Research Publications

  • Rao Gajula, S.N., Talari, S., Chilvery, S., Godugu, C. and Sonti, R., 2023. A unique in vivo pharmacokinetic profile, in vitro metabolic stability and hepatic first-pass metabolism of garcinol, a promising novel anticancer phytoconstituent, by liquid chromatography–mass spectrometry. RPS Pharmacy and Pharmacology Reports, 2(2), p.rqad017.
  • Rao Gajula, S.N., Talari, S., Nathani, T.N., Munjal, V., Rahman, Z., Dandekar, M.P. and Sonti, R., 2023. Effect of chronopharmacology and food on in vivo pharmacokinetic profile of mavacamten. Bioanalysis, 15(12), pp.695-706.
  • Dandekar, M.P., Palepu, M.S.K., Satti, S., Jaiswal, Y., Singh, A.A., Dash, S.P., Gajula, S.N.R. and Sonti, R., 2022. Multi-strain probiotic formulation reverses maternal separation and chronic unpredictable mild stress-generated anxiety-and depression-like phenotypes by modulating gut microbiome–brain activity in rats. ACS Chemical Neuroscience, 13(13), pp.1948-1965.
  • Anchi, P., Chilvery, S., Tekalkar, S., Gajula, S.N.R., Sonti, R. and Godugu, C., 2022. Nimbolide loaded sustained release microparticles as single-dose formulations for effective management of arthritis. Journal of Drug Delivery Science and Technology, 75, p.103638.
  • Satti, S., Palepu, M.S.K., Singh, A.A., Jaiswal, Y., Dash, S.P., Gajula, S.N.R., Chaganti, S., Samanthula, G., Sonti, R. and Dandekar, M.P., 2023. Anxiolytic-and antidepressant-like effects of Bacillus coagulans Unique IS-2 mediate via reshaping of microbiome gut-brain axis in rats. Neurochemistry International, 163, p.105483.

Expertise

  • Check Icon Conducting Drug metabolism and Pharmacokinetics (DMPK) studies
  • Check Icon Metabolomics and glycomics based disease biomarkers identification and quantification
  • Check Icon Handling of LC-MS/MS and other analytical instruments
  • Check Icon Structural characterization of small molecules
  • Check Icon Conducting various studies involved in drug development

Authored Books

  • Check Icon Handbook of Oxidative Stress in Cancer: Mechanistic Aspects
  • Check Icon Medicinal and Aromatic Plants
  • Check Icon Dosage Forms-Innovation and Future Perspectives
  • Check Icon Nanocarrier Vaccines: Biopharmaceutics‐Based Fast Track Development
  • Check Icon SARS-CoV-2 Variants and Global Population Vulnerability
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