rkumar2@gitam.edu
Dr. Kumar obtained his Ph.D. (Gold Medalist) from All India Institute of Medical Sciences, New Delhi, India and recipient of prestigious American Heart Association Postdoctoral Fellowship. His primary research focus is on understanding the physiological and molecular mechanisms underlying aging and age-related diseases including dementia and stroke. He uses various in vivo and in vitro approaches to o identify new biomarkers and develop novel therapeutics to treat age-related disorders.
Research Publications
- Mechanistic and therapeutic role of NLRP3 inflammasome in the pathogenesis of Alzheimer's disease.
- DNase 1 Protects From Increased Thrombin Generation and Venous Thrombosis During Aging: Cross-Sectional Study in Mice and Humans.
- Design, synthesis of allosteric peptide activator for human SIRT1 and its biological evaluation in cellular model of Alzheimer's disease
- Sirtuin1: a promising serum protein marker for early detection of Alzheimer’s disease.
- Identification of serum sirtuins as novel noninvasive protein markers for frailty
Ongoing Research Projects
-
Homocysteine and Post-Stroke Cognitive Decline: Unravelling the Neurovascular nexus
