proy@gitam.edu
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Prof. Roy research focuses on nanotechnological interventions in medicine and drug delivery. He is an expert in formulation development and development of newer arsenals for cell-imaging. His research interest includes engineered polymeric and metal nanoparticles to manage complex clinical conditions like triple negative breast cancer and drug resistance. Currently he is experimenting with carbon/ gold nanomaterials as newer arsenals in therapy and diagnostics.
Research Publications
- S Mal, T Saha, A Halder, S K Paidesetty, S Das, W T Wui, U Chatterji, P Roy. EGF-conjugated bio-safe luteolin gold nanoparticles induce cellular toxicity and cell death mediated by site-specific rapid uptake in human triple negative breast cancer cells. Journal of Drug Delivery Science and Technology. 80, 2023,104148.
- P Roy, V S Bhat, S Saha, D Sengupta, S Das, S Datta, G. Hegde. Mesoporous carbon nanospheres derived from agro-waste as novel antimicrobials agents against Gram- negative bacteria. Environmental Science and Pollution Research. 2020. 28(11):13552- 13561.
- A Halder, P Mukherjee, S Ghosh, A Mukherjee, S Das, P Roy, U Chatterji and A Mukherjee. Lactoferrin-tethered betulinic acid nanoparticles promote rapid delivery and cell death in triple negative breast and laryngeal cancer cells. Artificial Cells, Nanomedicine, and Biotechnology. 2020, 48(1):1362-1371.
- S Das, P Roy, T Bera and A Mukherjee. One pot synthesis of gold nanoparticles and application in chemotherapy of wild and resistant type visceral Leishmaniasis. Colloid and Surface B: Biointerface. 2013, 107, 27-34.
- Mal S, Chakraborty S, Mahapatra M, Pakeeraiah K, Das S, Paidesetty SK, Roy P. Tackling breast cancer with gold nanoparticles: twinning synthesis and particle engineering with efficacy. Nanoscale Adv. 2024 Apr 17;6(11):2766-2812.
Ongoing Research Projects
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Luteolin and Tazarotene co-loaded novel spanlastic fluidized nanovesicles engineered with Vit-E TPGS for smart combination therapy assisted improved management of psoriasis funded by Royal Society of Chemistry ((C23-6330916213)
Expertise
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Formulation development
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Site-specific Nanoparticle drug delivery
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Anti cancer, Antidiabetic, Hepatoprotective Nanotherapeutics
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Cell Imaging
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Plant Bioactive Based Engineered Nanomedicines
Authored Books
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Nil
