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Nalla Lakshmi Vineela

Nalla Lakshmi Vineela

Assistant Professor

Education

Ph. D.

As a Pharmacologist her academic focus centers on understanding the complexities of cancer, its mechanisms, and potential treatments. She earned the esteemed Kommareddy Venkata Sadasiva Rao Gold Medal as the top performer in her B. Pharm program. She received GPAT and NIPER-JEE fellowships from the Indian government for her M.S. (Pharm.) at NIPER-Mohali and Ph.D. at NIPER-Ahmedabad. She was a recipient of India's most prestigious Rajnibhai V. Patel PharmInnova Award for the year 2023-2024.

Research Publications

  • Nalla, L.V. and Khairnar, A., 2024. Empagliflozin drives ferroptosis in anoikis-resistant cells by activating miR-128-3p dependent pathway and inhibiting CD98hc in breast cancer. Free Radical Biology & Medicine, 220, pp.288-300. (IF-7.9)
  • Nalla, L.V. and Khairnar, A., 2023. Empagliflozin mediated miR-128-3p upregulation promotes differentiation of hypoxic cancer stem-like cells in breast cancer. European Journal of Pharmacology, 943, p.175565. (IF: 5)
  • Nalla, L.V., Gondaliya, P., Kalia, K. and Khairnar, A., 2022. Targeting specificity protein 1 with miR-128-3p overcomes TGF-β1 mediated epithelial-mesenchymal transition in breast cancer: An in vitro study. Molecular Biology Reports, 49(7), pp.6987-6996. (IF: 2.8)
  • Nalla, L.V., Dharavath, A., Behera, S.K. and Khairnar, A., 2023. Alpha mangostin inhibits proliferation, migration, and invasion of human breast cancer cells via STAT3 inhibition. Advances in Cancer Biology-Metastasis, 7, p.100089. (IF: 2.0)
  • Rihan, M., Nalla, L.V., Dharavath, A., Patel, S., Shard, A. and Khairnar, A., 2022. Boronic acid derivative activates pyruvate kinase M2 indispensable for redox metabolism in oral cancer cells. Bioorganic & Medicinal Chemistry Letters, 59, p.128539. (IF: 2.7)

Expertise

  • Check Icon Role of tumor microenvironment in cancer metastasis
  • Check Icon Senescence associated cancer progression
  • Check Icon Lifestyle induced cancer risk
  • Check Icon Partners for immune escape
  • Check Icon Impact of Glycomics on cancer progression

Authored Books

  • Check Icon Nanocarrier Vaccines: Biopharmaceutics‐Based Fast Track Development,
  • Check Icon SARS-CoV-2 Variants and Global Population Vulnerability
  • Check Icon Essentials of Pharmatoxicology in Drug Research, Volume 1
  • Check Icon Pharmacokinetics and Toxicokinetic Considerations
  • Check Icon Public Health and Toxicology Issues Drug Research, Volume 2
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