I have been working in Cellular and Molecular Biology of Infectious Diseases after earning a doctorate from Jawaharlal Nehru University, India. With 30 peer-reviewed articles in esteemed journals like Autophagy and Frontiers in Immunology, I am trying to make significant contributions to understanding TB pathomechanisms and microbial pathogenesis. I also act as a reviewer for journals like Frontiers and Scientific Reports and am a review editor for Gut Pathogens.
Research Publications
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Shariq M, Quadir N, Sharma N, et al. Mycobacterium tuberculosis RipA Dampens TLR4-Mediated Host Protective Response Using a Multi-Pronged Approach Involving Autophagy, Apoptosis, Metabolic Repurposing, and Immune Modulation. Front Immunol. 2021;12:636644.
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Sharma N, Shariq M, Quadir N, et al. Mycobacterium tuberculosis Protein PE6 (Rv0335c), a Novel TLR4 Agonist, Evokes an Inflammatory Response and Modulates the Cell Death Pathways in Macrophages to Enhance Intracellular Survival. Front Immunol. 2021;12:696491.
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Shariq M, Quadir N, Alam A, et al. The exploitation of host autophagy and ubiquitin machinery by Mycobacterium tuberculosis in shaping immune responses and host defense during infection. Autophagy. 2023 Jan;19(1):3-23.
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Quadir N, Shariq M, Sheikh JA, et al. Mycobacterium tuberculosis protein MoxR1 enhances virulence by inhibiting host cell death pathways and disrupting cellular bioenergetics. Virulence. 2023 Dec;14(1):2180230.
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Shariq M, Malik AA, Sheikh JA, et al. Regulation of autophagy by SARS-CoV-2: The multifunctional contributions of ORF3a. J Med Virol. 2023 Jul;95(7):e28959.
Expertise
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Infection Biology; Host-pathogen interaction; Innate immunity; Host-directed therapy; Drug-repurposing
Authored Books
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Exploration of the Mycobacterial Proteome in the Pathogenesis of TB: A Perspective.
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Repurposing Drugs for Effective Treatment of Tuberculosis: A Promising Approach