mthondam@gitam.edu
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Manjunatha Thondamal is an Associate Professor at Department of Biotechnology, GST. He received his Ph.D. from the ENS de Lyon, France in 2014. He was a postdoctoral research associate at University of Rochester, NY USA. Before joining GITAM, he served as DST INSPIRE Faculty at DRILS Hyderabad and at SRM University AP. He is a visiting scientist at Institute Pasteur, Paris. His research group at GITAM mainly focuses on the genetics of aging using C. elegans as model system.
Research Publications
- Thondamal, M., Witting, M., Schmitt-Kopplin, P., and Aguilaniu, H. “Steroid hormone signalling links reproduction to lifespan in dietary restricted Caenorhabditis elegans” Nat. Comm. 2014. https://doi.org/10.1038/ncomms5879
- Shamalnasab M, Dhaoui M, Thondamal M, Harvald EB, Færgeman N, Aguilaniu H, and Fabrizio P.
- Balamurugan, K., Medishetti, R., Kotha, J Behera, P., Chandra, K., Mavuduru, A., Joshi, M., Ramesh Samineni, R., Katika, M, Ball, W, Thondamal, M., Challa, A., Chatti, K., & Parsa, K. (2022). PHLPP1 promotes neutral lipid accumulation through AMPK/ChREBP-dependent lipid uptake and fatty acid synthesis pathways. iScience, 25(2), 103766. https://doi.org/10.1016/j.isci.2022.10376
- Chandra, K., Keerthana, S., Gopan, S., Ghantasala, J., Joshi, M., Thondamal, M., Kishore V.L. Parsa, K. PHLPP1 regulates PINK1-parkin signalling and life span. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Volume 1869, Issue 6, 2023, 166718. https://doi.org/10.1016/j.bbadis.2023.166718
- Busi KB, Palanivel M, Kotha J, Zoey FL, Zahid S, Ghosh KH, Agrawalla BK, Gulyas B, Halkarni S, Thondamal M, Padmanabhan P, Chakrabortty S. Potential impact of various surface ligands on the cellular uptake and biodistribution characteristics of red, green, and blue emitting Cu nanoclusters. RSC Adv. 2023, 13, 25862-25870
Ongoing Research Projects
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Genetics of DR mediated longevity
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Mitochondrial Morphology and Aging
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molecular basis of memory across animal kingdom
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Functional nanomaterials in health and aging
Expertise
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Creation of human disease models in C. elegans by using conventional transgenic techniques and CRISPR.
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Confocal Microscopy
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Reverse Genetics
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Assay development for drug screening in small animal models
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Behavioral (helathspan) and toxicity assay development for testing nanomaterials developed for biomedical applications
