mmukthin@gitam.edu
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Prof. Mathrusri Annapurna Mukthinuthalapati is from Visakhapatnam, Andhra Pradesh. She did her PhD (2006) from Berhampur University, Odisha. Her research interests are
• Analytical method development and validation of drugs using Spectrophotometry, HPLC, UFLC, UPLC, LC-MS/MS, FTIR
• Forced degradation studies
• Impurity profiling & Related substances
• QbD (Quality by Design)
• Study of Metal Complexes of drug molecules using SCPHD and MINIQUAD 75 programs
Research Publications
- Development and validation of a stability indicating RP-HPLC method for the determination of Febuxostat (Xanthine Oxidase Inhibitor) Journal of Chromatographic Science, 2013, Nov-Dec; 51(10):931-938. DOI:10.1093/chromsci/bms192
- Simultaneous determination of anti-diabetic drugs in their combined dosage forms using HPLC: An experimental design approach Journal of Chromatographic Science, 2019, 57(4), 339-348. DOI: 10.1093/chromsci/bmz003.
- Development and validation of a stability indicating RP-HPLC method for the determination of Rufinamide. Journal of Pharmaceutical Analysis, February 2013, 3(1), 66-70. DOI: 10.1016/j.jpha.2012.08.003
- Development and validation of the stability-indicating LC-UV method for the determination of Cefditoren pivoxil. Journal of Pharmaceutical Analysis, 2012, 2(6), 466-469. DOI: 10.1016/j.jpha.2012.06.003
- Stability-indicating liquid chromatographic method for the determination of Letrozole in pharmaceutical formulations Journal of Pharmaceutical Analysis, 2012, 2(4), 298-305. DOI:10.1016/j.jpha.2012.01.010
Expertise
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Method development and validation of drug molecules
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Spectrophotometry
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LC-MS/MS -Impurity profiling
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Forced degradation studies
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Chiral separations and Chiral chromatography
Authored Books
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Development and Validation of Analytical Methods for the Assay of Selected Drugs in Pharmaceutical
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Contd. ...Dosage forms and Biological fluids
