Kongara Hanumantha Rao

Assistant Professor

Department of Life Sciences

GITAM School of Science

Visakhapatnam

Education

Ph. D.

Dr K. Hanumantha Rao did his PhD from Jawaharlal Nehru University and Postdoc from NIPGR-DBT, New Delhi. His group is interested in understanding the fundamental cellular processes in Eukaryotes and Prokaryotes using molecular biology, biochemistry, and Bioinformatics tools in Candida, Vibrio, and Human-cell lines as model systems. The team is also trying to dissect molecular-mechanism pathogenesis in Fungi and Bacteria by adopting tools like Single-Cell RNAseq analysis, multi-omics approach

Research Publications

  • 1.Sahoo S, and Rao KH*. 2024. Role of carbon and nitrogen assimilation in Candida albicans survival and virulence. The Microbe. 4: 100127
  • 2. Sahoo S, Sharma S, Singh MP, Singh SK, Vamanu E, Rao KH*. 2023. Metabolic and Phenotypic Changes Induced during N-Acetylglucosamine Signalling in the Fungal Pathogen Candida albicans. Biomedicines. 11(7):1997.
  • 3. Rao KH*; Soumita Paul and Swagata Ghosh. 2022. N-acetylglucosamine kinase, Hxk1is a multifaceted metabolic enzyme in model pathogenic yeast Candida albicans. Microbiological Research.263: 127146.
  • 4. Rao KH*; Kasturi Roy; and Swagata Ghosh. 2022. Srg1, a putative protein phosphatase from the HAD-family proteins, is involved in stress adaptation in Candida albicans BBA General Subjects. 1866(8):130164
  • 5. Rao KH*; Kasturi Roy; Soumita Paul and Swagata Ghosh. 2022. N-acetylglucosamine transporter, Ngt1, undergoes sugar-responsive endosomal trafficking in Candida albicans. Molecular Microbiology. 117(2):429-449.

Ongoing Research Projects

  • Check Icon 1. DST SERB-CRG:.1.“Integrative Biological Approaches to unravel the central Role of Metabolism in Cell fate determination for Development of Novel Therapeutic Targets to combat Fungal Diseases” . Rs 61,00,000
  • Check Icon 2. SEED Grant Project.: Role of Arrestin-Related Trafficking adaptor (ART) Proteins in Endosomal Trafficking of Candida albicans. Funding agency: GITAM- Rs 5.0 lakh

Expertise

  • Check Icon Protein-Protein and Protein-DNA Interactions
  • Check Icon Bioinformatics and Computational Biology (Structural Biology & Systems Biology)
  • Check Icon Single Cell RNAseq analysis
  • Check Icon Multiomics (Genomics, Proteomics & Metabolomics)
  • Check Icon Time-lapse microscopy and FRET analysis
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