bsahoo@gitam.edu
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Dr. Sahoo received his Ph.D. degree from IIT Kharagpur. In the broad research domain of Biophysical Chemistry, the specific focus is on the following areas.
(1) Biomolecular interaction of small molecules with biomolecules
(2) Biomolecule denaturation and structure analysis
(3) Enzyme kinetics and inhibition studies
(4) Studies on the biological activity (antioxidant, antiglycation, anti-fibrillation and anti-amyloid and anti-angiogenesis) of molecules
(5) Drug repurposing studies
Research Publications
- Minor groove binding of antihistamine drug bilastine with calf thymus DNA: A molecular perspective with thermodynamics using experimental and theoretical methods, Journal of Molecular Structure, 1301 (2024). https://doi.org/10.1016/j.molstruc.2023.137385
- Steady-state and 3D fluorescence study reveals the binding of a dicoumarol analogue in subdomain IIA of human serum albumin with structural variation, Journal of Molecular Structure, 1298 (2024). https://doi.org/10.1016/j.molstruc.2023.137032
- Assessing Partial Inhibition of Ribonuclease A Activity by Curcumin through Fluorescence Spectroscopy and Theoretical Studies, Journal of Fluorescence (2023). https://doi.org/10.1007/s10895-023-03474-y
- Biophysical insights on the interaction of anticoagulant drug dicoumarol with calf thymus-DNA: deciphering the binding mode and binding force with thermodynamics, Journal of Biomolecular Structure and Dynamics, (2023). https://doi.org/10.1080/07391102.2023.2199872
- A comprehensive biophysical and theoretical study on the binding of dexlansoprazole with human serum albumin, Journal of Molecular Liquids, 380 (2023). https://doi.org/10.1016/j.molliq.2023.121777
Expertise
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(1) UV-Visible spectrophotometer, (2) Fluorescence spectrophotometer, (3) CD spectrophotometer, (4) Molecular docking, (5) Spectral data analysis
