amishra3@gitam.edu
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Dr. Amrendra Mishra earned his Ph.D. from Hannover Medical School, Germany, specializing in cancer research. Dr. Mishra, did his Postdoctoral training with Prof. Valter D. Longo at the University of Southern California, USA, during which he authored several significant preclinical and clinical studies focusing on aging, nutrition, cardiovascular risk factors and longevity. He is interested in exploring dietary interventions and genetics regulating aging, metabolism, and diseases.
Research Publications
- *Guevara-Aguirre, J., *Mishra, A., Canepa, M., Guevara, C., Villacres, Á., Guevara, A., Peña, G., Lescano, D., Kopchick, J. J., Balasubramanian, P., & Longo, V. D. (2024). Normal or improved cardiovascular risk factors in IGF-I-deficient adults with growth hormone receptor deficiency. Med. https://doi.org/10.1016/j.medj.2024.03.022 *equal contribution.
- Mishra, A., Giuliani, G., & Longo, V. D. (2024). Nutrition and dietary restrictions in cancer prevention. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1879(1), 189063. https://doi.org/10.1016/j.bbcan.2023.189063
- *Mishra, A., *Fanti, M., Ge, X., Vaughn, D., Brandhorst, S., Wei, M., Hong, K. M., Pellegrini, M., Pijl, H., Houston, M. C., & Longo, V. D. (2023). Fasting mimicking diet cycles versus a Mediterranean diet and cardiometabolic risk in overweight and obese hypertensive subjects: A randomized clinical trial. Npj Metabolic Health and Disease, 1(1), 1. https://doi.org/10.1038/s44324-023-00002-1 *equal contribution.
- *Mishra, A., *Mirzaei, H., *Guidi, N., Vinciguerra, M., Mouton, A., Linardic, M., Rappa, F., Barone, R., Navarrete, G., Wei, M., Brandhorst, S., Di Biase, S., Morgan, T. E., Ram Kumar, S., Conti, P. S., Pellegrini, M., Bernier, M., de Cabo, R., & Longo, V. D. (2021). Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan. Nature Metabolism, 3(10), 1342–1356. https://doi.org/10.1038/s42255-021-00469-6 *equal contribution.
- Mishra, A., Emamgholi, F., Erlangga, Z., Hartleben, B., Unger, K., Wolff, K., Teichmann, U., Kessel, M., Woller, N., Kühnel, F., Dow, L. E., Manns, M. P., Vogel, A., Lowe, S. W., Saborowski, A., & Saborowski, M. (2020). Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing. Carcinogenesis, 41(3), 334–344. https://doi.org/10.1093/carcin/bgz108
Expertise
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Aging biology
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Metabolism and aging
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Fasting and metabolism
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Fasting and dietary intervention for healthy aging and longevity
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CRISPR/Cas9 based in-vitro and in-vivo gene editing
