Siva Nageswararao Gajula

Assistant Professor, GSP, VSP

sgajula@gitam.edu | | | |

Experienced pharmaceutical researcher specialized in drug metabolism and pharmacokinetics (DMPK) studies with proficiency in LC-MS/MS analysis. Skilled in small molecule structural characterization, biomarker quantification, and phytoconstituent identification. Holds a Ph.D. from NIPER Hyderabad and M.S. (Pharm.) from NIPER Ahmedabad. Recipient of merit-based scholarships and awards, demonstrating a strong commitment to academic excellence and scientific research.

Research Publications
  • Rao Gajula, S.N., Talari, S., Chilvery, S., Godugu, C. and Sonti, R., 2023. A unique in vivo pharmacokinetic profile, in vitro metabolic stability and hepatic first-pass metabolism of garcinol, a promising novel anticancer phytoconstituent, by liquid chromatography–mass spectrometry. RPS Pharmacy and Pharmacology Reports, 2(2), p.rqad017.
  • Rao Gajula, S.N., Talari, S., Nathani, T.N., Munjal, V., Rahman, Z., Dandekar, M.P. and Sonti, R., 2023. Effect of chronopharmacology and food on in vivo pharmacokinetic profile of mavacamten. Bioanalysis, 15(12), pp.695-706.
  • Dandekar, M.P., Palepu, M.S.K., Satti, S., Jaiswal, Y., Singh, A.A., Dash, S.P., Gajula, S.N.R. and Sonti, R., 2022. Multi-strain probiotic formulation reverses maternal separation and chronic unpredictable mild stress-generated anxiety-and depression-like phenotypes by modulating gut microbiome–brain activity in rats. ACS Chemical Neuroscience, 13(13), pp.1948-1965.
  • Anchi, P., Chilvery, S., Tekalkar, S., Gajula, S.N.R., Sonti, R. and Godugu, C., 2022. Nimbolide loaded sustained release microparticles as single-dose formulations for effective management of arthritis. Journal of Drug Delivery Science and Technology, 75, p.103638.
  • Satti, S., Palepu, M.S.K., Singh, A.A., Jaiswal, Y., Dash, S.P., Gajula, S.N.R., Chaganti, S., Samanthula, G., Sonti, R. and Dandekar, M.P., 2023. Anxiolytic-and antidepressant-like effects of Bacillus coagulans Unique IS-2 mediate via reshaping of microbiome gut-brain axis in rats. Neurochemistry International, 163, p.105483.
Authored Books
  • Handbook of Oxidative Stress in Cancer: Mechanistic Aspects
  • Medicinal and Aromatic Plants
  • Dosage Forms-Innovation and Future Perspectives
  • Nanocarrier Vaccines: Biopharmaceutics‐Based Fast Track Development
  • SARS-CoV-2 Variants and Global Population Vulnerability
Expertise
  • Conducting Drug metabolism and Pharmacokinetics (DMPK) studies
  • Metabolomics and glycomics based disease biomarkers identification and quantification
  • Handling of LC-MS/MS and other analytical instruments
  • Structural characterization of small molecules
  • Conducting various studies involved in drug development
Siva Nageswararao Gajula