Faculty Profile

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Santosh Kumar Sahoo

Assistant Professor, GSP, VSP

ssahoo4@gitam.edu | | | |

Santosh Kumar Sahoo is from Bhubaneswar, Odisha. He holds a Ph.D. in Medicinal Chemistry from NIPER, Hyderabad. He has pharmaceutical industry experience as a Quality Control (Q.C.) officer, besides his research expertise in organic synthesis and Medicinal Chemistry. His research areas include the structure-based design of novel antibacterial and anticancer agents targeting drug resistance.

Research Publications

Synthesis and structure-activity relationship of new chalcone linked 5-phenyl-3-isoxazolecarboxylic acid methyl esters potentially active against drug resistant Mycobacterium tuberculosis. European Journal of Medicinal Chemistry 2021, 222, 113580. https://doi.org/10.1016/j.ejmech.2021.113580.
Bioevaluation of quinoline-4-carbonyl derivatives of piperazinyl-benzothiazinones as promising antimycobacterial agents. Archiv der pharmazie 2022, 355, 11, 2200168. https://doi.org/10.1002/ardp.202200168.
Identification of nitrofuranylchalcone tethered benzoxazole-2-amines as potent inhibitors of drug resistant Mycobacterium tuberculosis demonstrating bactericidal efficacy. Bioorganic & Medicinal Chemistry 2022, 64, 116777. https://doi.org/10.1016/j.bmc.2022.116777.
Synthesis of a new series of quinoline/pyridine indole-3-sulfonamide hybrids as selective carbonic anhydrase IX inhibitors. Bioorganic & Medicinal Chemistry Letters 2022, 70, 128809. https://doi.org/10.1016/j.bmcl.2022.128809.
Biomimetic synthesis, characterization and mechanism of formation of stable silver nanoparticles using Averrhoa carambola L. leaf extract. Materials Letters 2015, 160, 566-571. https://doi.org/10.1016/j.matlet.2015.08.048.

Ongoing Research Projects

Structure-based design and bio-evaluation of pyrazole/indole-based novel bacterial topoisomerase inhibitors as promising chemotypes to combat drug-resistant infection.

Expertise

Structure-based Drug Design and Discovery
Medicinal Chemistry and Chemical Biology
Novel Antibacterial and Anticancer Chemotherapeutics Development
Hit-to-Lead optimization for Biologically active compound

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About

Santosh Kumar Sahoo

Assistant Professor, GSP, VSP

Research Publications

Ongoing Research Projects

Expertise

Hyderabad City Office

Bengaluru City Office