Faculty Profile

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Kancharla Bhanukiran

Assistant Professor, GSP, VSP

bkanchar@gitam.edu | | | |

Dr. Bhanukiran K has achieved his Master's and PhD degrees specializing in Pharmacognosy and Phytochemistry from the IIT (BHU), Varanasi. Throughout his research, he explored various natural products and their semi-synthetic derivatives. Additionally, he delved into computational tools such as molecular docking, dynamics simulations, and DFT studies as part of his investigative approach. His current professional endeavors are centered on natural products in drug discovery.

Research Publications

Bhanukiran, K., Singh, S.K., Singh, R., Kumar, A. and Hemalatha, S., 2023. Discovery of Multitarget-Directed Ligands from Piperidine Alkaloid Piperine as a Cap Group for the Management of Alzheimer’s Disease. ACS Chemical Neuroscience, 14(15).
Bhanukiran, K., Gajendra, T.A., Krishnamurthy, S., Singh, S.K. and Hemalatha, S., 2023. Discovery of multi-target directed 3-OH pyrrolidine derivatives through a semisynthetic approach from alkaloid vasicine for the treatment of Alzheimer's disease. European Journal of Medicinal Chemistry, 249, p.115145.
Bhanukiran, K. and Hemalatha, S., 2024. Single crystal X-ray, DFT, molecular dynamic simulations, and biological evaluation of 3-OH pyrrolidine derivative VA10 from alkaloid vasicine for BACE1 inhibition. Journal of Molecular Structure, 1300(15), p.137196.
Bhanukiran, K., Singh, R., Gajendra, T.A., Ramakrishna, K., Singh, S.K., Krishnamurthy, S., Kumar, A. and Hemalatha, S., 2023. Vasicinone, a pyrroloquinazoline alkaloid from Adhatoda vasica Nees enhances memory and cognition by inhibiting cholinesterases in Alzheimer's disease. Phytomedicine Plus, 3(2), p.100439.
Bhanukiran, K., Dubey, T. and Hemalatha, S., 2022. Quality Control Standardization and in-vitro Antioxidant Activity of Marsilea quadrifolia Linn. Pharmacognosy Research, 14(2).

Expertise

Standardization of Herbal Drugs
Bio-activity Guided Fractionation
Isolation of Bioactive Compounds
Design and Synthesis of Semi-synthetic Derivatives
Computer-Aided Drug Design and Network Pharmacology

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About

Kancharla Bhanukiran

Assistant Professor, GSP, VSP

Research Publications

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Hyderabad City Office

Bengaluru City Office